Meso-relle Mesotherapy needles are extremely thin and precisely sharpened, so patient discomfort is minimal. Mesotherapy is one of the most sought-after facial treatments in recent years and works by injecting ingredients into the mesoderm, the middle layer of the skin, using very fine and specially designed needles. They are individually sterile, blister-packed, disposable, and feature a cap that covers the needle before and after use to prevent injuries. They are made in Italy. Bases for the needles, circular or linear with 3 & 5 positions, are also available.